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"path": "/abs/2603.26176v1",
"publishedAt": "2026-03-30T00:00:00.000Z",
"site": "https://arxiv.org",
"tags": [
"Ryosuke Yamano",
"Tetsuo Shibuya"
],
"textContent": "**Authors:** Ryosuke Yamano, Tetsuo Shibuya\n\nThe Shortest Common Superstring (SCS) problem is a fundamental task in sequence analysis. In genome assembly, however, the double-stranded nature of DNA implies that each fragment may occur either in its original orientation or as its reverse complement. This motivates the Shortest Common Superstring with Reverse Complements (SCS-RC) problem, which asks for a shortest string that contains, for each input string, either the string itself or its reverse complement as a substring. The previously best-known approximation ratio for SCS-RC was $\\frac{23}{8}$. In this paper, we present a new approximation algorithm achieving an improved ratio of $\\frac{8}{3}$. Our approach computes an optimal constrained cycle cover by reducing the problem, via a novel gadget construction, to a maximum-weight perfect matching in a general graph. We also investigate the computational hardness of SCS-RC. While the decision version is known to be NP-complete, no explicit inapproximability results were previously established. We show that the hardness of SCS carries over to SCS-RC through a polynomial-time reduction, implying that it is NP-hard to approximate SCS-RC within a factor better than $\\frac{333}{332}$. Notably, this hardness result holds even for the DNA alphabet.",
"title": "Improved Approximation Algorithms and Hardness Results for Shortest Common Superstring with Reverse Complements"
}