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  "path": "/articles/s41586-026-10612-6",
  "publishedAt": "2026-06-04T02:16:37.414Z",
  "site": "https://www.nature.com",
  "tags": [
    "doi:10.1038/s41586-026-10612-6"
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  "textContent": "Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10612-6\n\nLongitudinal transcriptomic, chromatin and genomic analyses of the two types of IDH-mutant glioma reveal in detail how disease progression is influenced by interdependent genetic, epigenetic and microenvironmental factors.",
  "title": "Acquired genetic and cell-state changes in IDH-mutant glioma progression",
  "updatedAt": "2026-06-03T00:00:00.000Z"
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