PtdIns(3,5)P<sub>2</sub> is an endogenous ligand of STING in innate immune signalling
Nature [Unofficial]
February 5, 2026
Nature, Published online: 04 February 2026; doi:10.1038/s41586-025-10084-0
Phosphatidylinositol 3,5-bisphosphate is a ligand of STING and, together with cGAMP, induces STING activation and innate immune responses.
Discussion in the ATmosphere